GEN-OBREAST
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GEN-OBREAST

20,000 EGP

evidence-based management and risk reduction options

GEN-OBREAST cancer test includes all genes that are associated with a significantly increased risk of developing breast cancer and for which there are medically actionable, evidence-based management and risk reduction options!

GEN-OBREAST is a targeted gene panel that utilizes next-generation sequencing (NGS) to analyze genes associated with hereditary breast cancer risk, identifying pathogenic variants and providing personalized risk assessments and management recommendations.

You will receive your report via Our Reports GEN-Portal within 45 business days.
    • Simple blood test
    • Personalized risk assessment
    • Extended family screening – if required
    • Management recommendations
Complimentary 30-minute genetic consultation included
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Description

Discover a new side to your personal history

What is Breast & Ovarian Cancer?

Breast & ovarian cancer are the most common cancers in women. 1 in 8 women will develop breast cancer in their lifetime.

Breast cancer occurs when the cells in the breast begin to grow abnormally into a malignant tumor. Hereditary breast cancer & ovarian occurs when a person has a genetic change (mutation) that causes their cells to be more likely to become cancerous. The mutation can be passed through generations in a family.

 

Who might need genetic testing for Hereditary Breast & Ovarian Cancer?

Hereditary breast & ovarian cancer testing is indicated if you or a close relative meet certain criteria. Your physician will make the final decision about testing based on your clinical and family history, but some “red flags” suspicious for hbc are listed below:

  • A family history of individuals with breast, pancreatic, prostate, melanoma, or other cancers, especially if early onset or if multiple cancers occurred in a single individual.
  • Breast cancer diagnosed before age 50 years
  • Known cancer-risk gene mutation in the family
  • Triple negative (ER-, PR-, HER2-) breast cancer before age 60 years.
  • Two primary breast cancers in a single individual
  • Breast cancer and either ovarian or pancreatic cancer in a single individual
  • Ovarian cancer

ACCURATE

99.9% Analytical Accuracy

TRUSTED

Over 4,000,000 tests carried out to date by clinicians in more than 80 countries

COMPREHENSIVE

Our Reports Portal is shows up to 500+ reports

SAFE

Encrypted Secure Data

SIMPLE

1-1 Genetic Consultation

What Our Clients Say...

Recommended to all pregnant women

Best service & doctors ever. After getting my GEN-NIPT results I felt so relieved and stress free to know that my baby is in great health while I'm only 12 weeks pregnant. I'm super satisfied that I did the test in my 3 pregnancies and I'd definitely recommend it to all pregnant women.

Nihal Shoukry
Mother of 3

My GEN-NIPT experience was nothing short of exceptional and is highly recommended. The team at Generations Genetics demonstrated a remarkable level of care and attention throughout the entire process. I felt comfortable and informed. After receiving the results, it was reassuring to be able to trust the accuracy of the results allowing me to focus on the joy of my pregnancy without unnecessary worry.

Sara El Gohary
Director of Marketing at Four Seasons

I did the GEN-LIFE test with Generations Genetics and the results were super interesting! The process was super simple. I ordered a home test kit, followed very clear instructions and voila! it was ready. I then received a link that gave me an insight into every important aspect of my life. From knowing my countries of origins, to what foods cause my anxiety, I found information that explained why certain sports are better for me and which creams I needed to use for my skin. Gen-life report was very detailed yet easy to read. There is also a free consultation offered with it. The test was incredible and the process with GG was very professional & user friendly.

Sarah Abdelmoneim
Founder of Sukun Studios
    • Comprehensively analyzes 20+ genes associated with hereditary breast cancer risk, including BRCA1, BRCA2, PALB2, CHEK2, ATM, TP53, PTEN, and CDH1, among others
    • Employs high-depth NGS technology (>500x coverage) to accurately detect single nucleotide variants (SNVs), small insertions/deletions (indels), and copy number variations (CNVs) in targeted genes
    • Utilizes advanced bioinformatics pipelines and variant interpretation algorithms based on ACMG guidelines and ClinVar database to classify variants based on their pathogenicity scores.
    • Offers evidence-based recommendations for breast cancer screening, risk-reducing strategies (e.g., enhanced surveillance, chemoprevention, prophylactic surgery), and targeted therapies (e.g., PARP inhibitors for BRCA-related cancers) based on individual genetic profile and clinical guidelines (e.g., NCCN, ASCO)
    • Includes pre- and post-test genetic counseling services to ensure informed consent, proper interpretation of results, and psychosocial support for patients and their families

Turn Around Time (TAT): 45 working days

Sample type: Simple Swab

Availability: Online (Home kit) or branch Visit 

Report: Online GEN-Portal

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